Neoplastic Disease: Anti-Cancer: Research and Development
Peer reviewed discussions associated
with molecular diagnostics, containment, treatment and control.
Contact: Stephen M. Apatow, Director of
Research and Development, Humanitarian University
Consortium Graduate Studies
Center for Medicine,
Medicine and Law.
In The Spotlight
Tumor Infiltrating Lymphocyte Therapy: A specific type of
cell transfer immunotherapy, in which the lymphocytes infused back into the
patient are from the patients own tumor. These lymphocytes are actually
infiltrating and trying to destroy the tumor and they are obtained when the
tumor is biopsied or excised. The tumor infiltrating lymphocytes contain
a large concentration of cytotoxic T lymphocytes specifically targeted against
the antigens in the patients own tumor as well as numbers of natural killer
lymphoctes that can destroy tumor cells . The lymphocytes are grown
in a laboratory with interleukin-2 to stimulate growth of the lymphocytes
and then infused back into the patient to attack and destroy the tumor.
-- Neoplastic Disease: An Introduction to Human Disease:
Pathology and Pathophysiology Correlations, Leonard V. Crowley.
In patients with high grade glioma,
little is known regarding existence of naturally occurring adaptive T cell
reactivity against glioma-associated antigens (GAAs). In this report, we
characterized GAA-specific CD8+ T cells and innate immune cells
in a patient who has survived with anaplastic astrocytoma (AA) for over
12 years without recurrence. -- Spontaneous immune responses against glioma-associated antigens
in a long term survivor with malignant glioma: Journal of Translational
Medicine 2007, 5:68.
Veterinary: Biologics, Anti-Cancer Research
Cell Wall-DNA complex (MCC), Oligonucleotides.
Human Medicine: Anti-Cancer Research